Although you may never have heard of the cytochrome P450 superfamily of enzymes, these proteins play diverse and critical roles in humans through the metabolic processing of drugs, pesticides, fatty ...

The ensemble-function approach provides a quantitative catalytic model for serine proteases and identifies repeatedly evolved catalytic strategies. Credit: Science (2025). DOI: 10.1126/science.ado5068 ...

A central question in molecular biology is how cells protect their chromosomes from damage during repeated cell division. At ...

A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...

UC Riverside researchers have identified a mechanism that allows plants to rapidly slow growth in response to extreme ...

The latest short science news items from C&EN. The team proposes that SAM plays a dual role in the reaction. It donates a methyl group to the enzyme’s cobalamin cofactor and then serves as a base when ...

Halogenated compounds are widespread in the pharmaceutical and agrochemical industries. But the reagents used to make them can produce hazardous waste and mixtures of compounds. Enzymes can provide a ...

Man prides himself upon his growing mastery over nature, but in the ultimate biochemical analysis nature remains the master of man. With their most sophisticated laboratory glassware and corrosive ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...